The Encyclopedia of Peptides

A to Z / Sexual health

hCG

Also known as human chorionic gonadotropin, Pregnyl, Ovidrel.

Best known for A proven fertility medicine, not supported for weight loss
Evidence★★★★☆
Safety dataWell characterised
Route injectable (subcutaneous · intramuscular)
United StatesFDA approved
AustraliaSchedule 4 (Prescription Only)
as at 16 September 2026

What it is

Human chorionic gonadotropin is a hormone produced in pregnancy: the one home pregnancy tests detect. As a medicine it is approved for fertility treatment and for certain forms of hypogonadism, with decades of clinical use.

It appears in this book for two reasons: it is used in testosterone replacement protocols to preserve testicular function, and it was the basis of a well-known weight-loss diet that has since been thoroughly tested and disproven.

What the full entry covers

The book carries the rest of this entry:

Related entries

A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.

This page describes what is known and not known about hCG. It is not medical advice and not a recommendation to use it.