The Encyclopedia of Peptides

A to Z / Sexual health

Gonadorelin

Also known as GnRH, LHRH, gonadotropin-releasing hormone.

Best known for The TRT adjunct that isn't hCG
Evidence★★★★☆
Safety dataWell characterised
Route Injectable
United StatesApproved (some formulations)
AustraliaSchedule 4
as at 16 September 2026

What it is

Gonadorelin is synthetic gonadotropin-releasing hormone: the natural ten-amino-acid signal from the hypothalamus that tells the pituitary to release LH and FSH. It has approved diagnostic and therapeutic uses, and is increasingly used off-label in testosterone replacement protocols as an alternative to hCG.

What the full entry covers

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Related entries

A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.

This page describes what is known and not known about Gonadorelin. It is not medical advice and not a recommendation to use it.