A to Z / Longevity
SS-31
Also known as Elamipretide, Bendavia, MTP-131.
Best known for The mitochondrial peptide with modern human trials
Evidence★★★☆☆
Safety dataModerately characterised
Route injectable (subcutaneous)
United StatesInvestigational
AustraliaNot listed by name; unapproved therapeutic good
as at 16 September 2026
What it is
SS-31, elamipretide, is a four-amino-acid peptide developed as a pharmaceutical for mitochondrial disease. It is the most clinically advanced mitochondrial-targeted compound in this book, with a full pharmaceutical development programme behind it. It is investigational and not yet approved.
What the full entry covers
The book carries the rest of this entry:
- Where the research stands, with every claim cited
- What people commonly ask, and what the research shows so far
- Dosing in four labelled bands, described and not recommended
- Side effects, serious risks, cautions and interactions
- Questions to discuss with your doctor
- How it compares with MOTS-c, Humanin, Epitalon
Related entries
A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.
This page describes what is known and not known about SS-31. It is not medical advice and not a recommendation to use it.