The Encyclopedia of Peptides

A to Z / Longevity

Epitalon

Also known as Epithalon, Epithalamin, AEDG peptide.

Best known for The telomere peptide
Evidence★☆☆☆☆
Safety dataLargely unknown
Route injectable (subcutaneous)
United StatesNot approved
AustraliaNot listed by name; unapproved therapeutic good
as at 16 September 2026

What it is

Epitalon is a four-amino-acid peptide (Ala-Glu-Asp-Gly) developed in the Soviet Union in the 1980s, derived from work on pineal gland extracts. It belongs to a family of Russian bioregulator peptides. It is not approved in Western markets, and there are no modern controlled trials yet.

It is one of the most widely discussed longevity peptides, with interest centred on its proposed effect on telomeres.

What the full entry covers

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Related entries

A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.

This page describes what is known and not known about Epitalon. It is not medical advice and not a recommendation to use it.