Reconstitution calculator / MOTS-c
MOTS-c reconstitution calculator
The arithmetic below is the same for any compound. What changes is the vial in front of you, so read its label and enter those numbers rather than numbers from anywhere else.
Worth knowing before you calculate anything. MOTS-c rates ★☆☆☆☆ on our evidence scale, and its safety profile is largely unknown.
A calculator will return a tidy number for any compound you give it. That number says nothing about whether the compound works, whether the dose is sensible, or whether the product in the vial is what the label claims.
Where the dose figure should come from
This page does not supply one. For MOTS-c the honest position is set by the evidence:
The book reports dose figures in four labelled bands, so you can always see whether a number comes from an approved label, from a published trial, from what circulates without trial support, or from nothing at all. That labelling matters more than the number.
If you have a certificate of analysis
Check whether it reports a net peptide content lower than the labelled weight. Peptides are usually supplied as a salt and hold water, so a vial labelled 5 mg can contain less than 5 mg of the peptide itself. Where that figure is given, it is the one to enter above.
The certificate describes what is in the vial. The evidence rating at the top of this page describes whether MOTS-c has been shown to work in humans. Neither answers the other's question.How to read a certificate of analysis.
What this page will not do
It will not tell you what to take or whether to take it, and it is not medical advice. Sterile technique, storage and the provenance of the vial matter as much as the arithmetic. What is actually known about storage.
About MOTS-c
MOTS-c is a mitochondrial-derived peptide: a short peptide encoded not by the cell nucleus but by mitochondrial DNA. Its discovery was an important scientific finding: mitochondria were not thought to produce signalling peptides that act on the rest of the body. Research so far is in mice, there are no human efficacy trials yet, and it is not approved as a medicine.
Educational reference, not medical advice, and not a recommendation to use MOTS-c. Edition 1.0. Regulatory information as at 16 September 2026. Calculator behaviour last reviewed 12 October 2026.