A to Z / Repair & recovery

TB-500

Also known as Thymosin Beta-4 fragment, TB500.

Best known for The other half of the "Wolverine Stack"

Evidence★★☆☆☆

Safety dataPoorly characterised

Route injectable (subcutaneous)

United StatesNot approved

AustraliaAppendix D, clause 5

as at 16 September 2026

What it is

TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring protein involved in cell migration and tissue repair. It is a piece of that protein, not the whole thing.{{CITE:rahaman-2024-tb500}} That distinction is often overlooked, and it is the most important fact on this page.

TB-500 has been studied mainly in animal models of healing and tissue repair. It is not approved anywhere yet, and supply today is mainly through research-chemical suppliers.

What the full entry covers

The book carries the rest of this entry:

Where the research stands, with every claim cited
What people commonly ask, and what the research shows so far
Dosing in four labelled bands, described and not recommended
Side effects, serious risks, cautions and interactions
Questions to discuss with your doctor
How it compares with BPC-157, Thymosin Beta-4, GHK-Cu, KPV

Related entries

BPC-157Tendon, joint and gut repair · Evidence ★★☆☆☆
Thymosin Beta-4The full protein that TB-500 is a fragment of · Evidence ★★☆☆☆
GHK-CuSkin renewal and collagen support · Evidence ★★☆☆☆
KPVThe gut and inflammation peptide with a rising profile · Evidence ★☆☆☆☆

A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.

This page describes what is known and not known about TB-500. It is not medical advice and not a recommendation to use it.