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Bremelanotide Analogues

Also known as melanocortin agonists, MC1R/MC3R/MC4R agonists.

Best known for The wider melanocortin family, and why selectivity decides everything

Evidence★★☆☆☆

Safety dataPoorly characterised

Route Injectable · nasal

United StatesVaries; most not approved

AustraliaVaries by compound; most unapproved

as at 16 September 2026

What it is and what it does

This entry covers the broader melanocortin agonist family: the class containing PT-141, Melanotan I, Melanotan II and setmelanotide, plus a range of research analogues available under various names. Three members are approved for narrow indications; most research analogues are unapproved and untested in humans.

These compounds are often confused with one another, and one principle, receptor selectivity, explains the entire family's behaviour.

What the full entry covers

The book carries the rest of this entry:

Where the research stands, with every claim cited
What people commonly ask, and what the research shows so far
Dosing in four labelled bands, described and not recommended
Side effects, serious risks, cautions and interactions
Questions to discuss with your doctor
How it compares with PT-141, Melanotan I, Melanotan II, Setmelanotide

Related entries

PT-141The approved libido medicine, also used outside prescription · Evidence ★★★★☆
Melanotan IThe melanotan that became an approved medicine · Evidence ★★★★☆
Melanotan IIThe injectable tanning peptide · Evidence ★☆☆☆☆
SetmelanotideThe melanocortin drug for rare genetic obesity · Evidence ★★★★★

A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.

This page describes what is known and not known about Bremelanotide Analogues. It is not medical advice and not a recommendation to use it.