The Encyclopedia of Peptides

A to Z / Approved medicine

Insulin

Also known as various brands; insulin glargine, lispro, degludec.

Best known for The original therapeutic peptide, with serious risks outside medical use
Evidence★★★★★
Safety dataWell characterised
Route Injectable
United StatesFDA approved
AustraliaSchedule 4: ARTG-registered
as at 16 September 2026

What it is

Insulin is a 51-amino-acid peptide hormone and the drug that started peptide medicine: first used in a patient in 1922. It is an essential medicine, on the WHO model list, and it keeps millions of people alive.

It appears here for two reasons: it is the reference point for what a peptide drug can be, and its non-medical use in bodybuilding carries a mortality rate unmatched by anything else in this book.

What the full entry covers

The book carries the rest of this entry:

Related entries

A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.

This page describes what is known and not known about Insulin. It is not medical advice and not a recommendation to use it.