A to Z / Cosmetic / skin
Hexapeptide-11
Also known as yeast-derived hexapeptide.
Best known for The anti-senescence cosmetic peptide
Evidence★★☆☆☆
Safety dataWell characterised
Route Topical
United StatesCosmetic ingredient: lawfully sold
AustraliaCosmetic ingredient: lawfully sold
as at 16 September 2026
What it is and what it does
Hexapeptide-11 is a six-amino-acid cosmetic peptide, originally identified from yeast fermentation, and a lawful cosmetic ingredient. It is studied for skin elasticity and firmness, and commonly discussed for “cellular ageing”.
What the full entry covers
The book carries the rest of this entry:
- Where the research stands, with every claim cited
- What people commonly ask, and what the research shows so far
- Dosing in four labelled bands, described and not recommended
- Side effects, serious risks, cautions and interactions
- Questions to discuss with your doctor
- How it compares with Matrixyl, GHK-Cu, Progeline, Decorinyl
Related entries
A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.
This page describes what is known and not known about Hexapeptide-11. It is not medical advice and not a recommendation to use it.