A to Z / Approved medicine
Enfuvirtide
Also known as Fuzeon, T-20.
Best known for The HIV drug that proved peptides can block a virus
Evidence★★★★★
Safety dataWell characterised
Route twice-daily subcutaneous injection
United StatesFDA approved
AustraliaSchedule 4: prescription only
as at 16 September 2026
What it is and what it does
Enfuvirtide is a 36-amino-acid peptide that physically blocks HIV from entering cells. It is an approved medicine, used in combination antiretroviral therapy for HIV, particularly where resistance to other agents has developed.
What the full entry covers
The book carries the rest of this entry:
- Where the research stands, with every claim cited
- What people commonly ask, and what the research shows so far
- Dosing in four labelled bands, described and not recommended
- Side effects, serious risks, cautions and interactions
- Questions to discuss with your doctor
- How it compares with Icatibant, Linaclotide
Related entries
A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.
This page describes what is known and not known about Enfuvirtide. It is not medical advice and not a recommendation to use it.