A to Z / Repair & recovery
Larazotide
Also known as AT-1001, larazotide acetate.
What it is
Larazotide is an eight-amino-acid peptide developed as a treatment for coeliac disease. It works locally in the gut and is not meaningfully absorbed: unusual and advantageous for an oral peptide.
Larazotide reached phase 3, further than almost any peptide in this section. It is not approved, and development was discontinued after that trial. It is the most clinically advanced compound associated with the “leaky gut” concept.
What the full entry covers
The book carries the rest of this entry:
- Where the research stands, with every claim cited
- What people commonly ask, and what the research shows so far
- Dosing in four labelled bands, described and not recommended
- Side effects, serious risks, cautions and interactions
- Questions to discuss with your doctor
- How it compares with KPV, BPC-157, VIP
Related entries
A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.
This page describes what is known and not known about Larazotide. It is not medical advice and not a recommendation to use it.