A to Z / Growth hormone

Ipamorelin

Best known for The "clean" growth hormone secretagogue

Evidence★★☆☆☆

Safety dataPoorly characterised

Route injectable (subcutaneous)

United StatesNot approved

AustraliaSchedule 4 + Appendix D, clause 5

as at 16 September 2026

What it is

Ipamorelin is a synthetic growth hormone secretagogue: a five-amino-acid peptide that triggers growth hormone release through the ghrelin receptor. Human research so far covers growth hormone release; it is not approved as a medicine. It is the most widely prescribed peptide in anti-ageing clinics, almost always paired with CJC-1295.

Its reputation rests on selectivity: unlike the older GHRPs, it releases growth hormone without meaningfully raising cortisol or prolactin.{{CITE:raun-1998}}

What the full entry covers

The book carries the rest of this entry:

Where the research stands, with every claim cited
What people commonly ask, and what the research shows so far
Dosing in four labelled bands, described and not recommended
Side effects, serious risks, cautions and interactions
Questions to discuss with your doctor
How it compares with CJC-1295 (with DAC), GHRP-2, GHRP-6, Hexarelin

Related entries

CJC-1295 (with DAC)Half of the classic clinic growth hormone stack · Evidence ★★☆☆☆
GHRP-2The older growth hormone secretagogue that raises cortisol · Evidence ★★☆☆☆
GHRP-6The secretagogue known for its strong effect on hunger · Evidence ★★☆☆☆
HexarelinThe strongest-acting secretagogue, with the fastest tolerance · Evidence ★★☆☆☆

A certificate of analysis tells you what is in a vial. The evidence rating above tells you whether the compound has been shown to work in humans. Neither answers the other's question. How to read a certificate of analysis.

This page describes what is known and not known about Ipamorelin. It is not medical advice and not a recommendation to use it.